FACTORS AFFECTING THE PHARMACOKINETICS AND PHARMACODYNAMICS OF PEGYLATED LIPOSOMAL IRINOTECAN (IHL-305) IN PATIENTS WITH ADVANCED SOLID TUMORS

Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors

Huali Wu,1 Jeffrey R Infante,2 Vicki L Keedy,3 Suzanne F Jones,2 Emily Chan,3 Johanna C Bendell,2 Wooin Lee,4 Whitney P Kirschbrown,1 Beth A Zamboni,5 Satoshi Ikeda,6 Hiroshi Kodaira,6 Mace L Rothenberg,3 Howard A Burris III,2 William C Zamboni1,7–9 1UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 2Sarah Cannon

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Selection and recommend of quinoa (Chenopodium quinoa) genotypes based on the yield genotypic adaptability and stability

ABSTRACT The present study aimed to select and recommend quinoa genotypes based on the yield genotypic adaptability and stability, by the method Beer Glass of the Harmonic mean of relative performance of genotypic values.Five experiments were conducted during the crop seasons of 2014 and 2015 in two locations in the Western region of Paraná State,

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